Michelson D, Allen AJ, Busner J et al. Once daily atomoxetine treatment for children and adolescents with attention deficit hyperactivity disorder: a randomized, placebo-controlled study. Am J Psychiatry. There are no adequate and well-controlled studies examining sexual dysfunction with STRATTERA treatment. While it is difficult to know the precise risk of sexual dysfunction associated with the use of STRATTERA, physicians should routinely inquire about such possible side effects. It's important to work with a doctor to find the best solution for your child. detrol
Do I need a prescription for atomoxetine? Minimal affinity for other noradrenergic receptors or for other neurotransmitter transporters or receptors. Thanks, and Good Luck!
STRATTERA did not worsen anxiety in these patients as determined by the Liebowitz Social Anxiety Scale LSAS. Of the 413 patients who completed the double-blind placebo lead-in, 149 36. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products.
Use caution when prescribing to patients with a history of drug dependence or alcoholism. Chronic abusive use can lead to marked tolerance and psychological dependence with abnormal behavior. Psychotic episodes can occur, especially with parenteral abuse. Carefully supervise withdrawal from abusive use to avoid the onset of severe depression. Importance of advising patient or caregiver that the drug is an ocular irritant and that the capsules should not be opened; if eye contact occurs, flush affected eyes with water immediately, obtain medical advice, and wash hands and potentially contaminated surfaces as soon as possible.
GPA in the hardest Mathematics sequence that exists on this planet. God Bless Ritalin. I hope that parents out there with a kid who fits this description of my past doesn't fall victim to the hype that this drug is destructive. Sure, any substance can be misused. However, if a doc recommends it for these symptoms in a person, it's worth a shot; a shot at life. My life is just beginning at and it could have started so long ago had this pharmaceutical solution been taken earlier on in my life. Look at the long-term studies of this drug. It's track record is good and my worst day on Ritalin is still better than my better days off of it. Exercise helps, Ritalin solves. If this becomes a permanent solution then so be it. I don't want to go back to the way it was. Do not share this medication with others. Heart-related problems have been reported with Strattera. Sudden death has been reported in patients who have heart problems or heart defects. There have also been reports of stroke and heart attack in adults, and increased blood pressure and heart rate. Tell your doctor if you or your child has any heart problems, heart defects, high blood pressure, or a family history of these problems. Your doctor should check you or your child carefully for heart problems before starting Strattera. Call your doctor right away if you or your child has any signs of heart problems such as chest pain, shortness of breath, or fainting while taking Strattera. Who should not take Strattera? It is not their fault that they cannot do these things. Do not take extra medicine to make up the missed dose. What happens if I overdose? Dr. Peter Yellowlees cont. Strattera is a noncontrolled substance, and studies have identified only isolated incidents of inappropriate self-administration, meaning it lacks the abuse potential and dependence risk seem with stimulant-type drugs such as Adderall. There is also no evidence of symptom rebound or withdrawal symptoms on drug discontinuation. Strattera may be useful in patients with ADHD and a comorbid substance abuse disorder or tic disorder. Do not crush, chew, or break an extended-release Ritalin SR tablet. Swallow the tablet whole. Breaking the tablet may cause too much of the drug to be released at one time. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs including any herbal medicines or supplements or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. At first, 5 mg two times a day, taken before breakfast and lunch. Your doctor may adjust your dose as needed. However, the dose is usually not more than 60 mg per day.
Store Strattera at room temperature, between 59 and 86 degrees F 15 and 30 degrees C. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Strattera out of the reach of children and away from pets. However, prior to initiating treatment with STRATTERA, patients with comorbid depressive symptoms should be adequately screened to determine if they are at risk for bipolar disorder; such screening should include a detailed psychiatric history, including a family history of suicide, bipolar disorder, and depression. Unlike many other used to treat ADHD, Straterra is not a stimulant. Instead, it works by boosting levels of the chemical norepinephrine, which helps reduce impulsive behavior and hyperactivity and increases attention span. Eli Lilly and Company. Available at Pediatrics website. Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. STRATTERA should be administered with caution to patients being treated with systemically-administered oral or intravenous or other beta 2 agonists because the action of albuterol on the can be potentiated resulting in increases in heart rate and blood pressure. Albuterol 600 mcg iv over 2 hours induced increases in heart rate and blood pressure. These effects were potentiated by atomoxetine 60 mg BID for 5 days and were most marked after the initial coadministration of albuterol and atomoxetine. However, these effects on heart rate and blood pressure were not seen in another study after the coadministration with inhaled dose of albuterol 200-800 mcg and atomoxetine 80 mg QD for 5 days in 21 healthy Asian subjects who were excluded for poor metabolizer status. Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of atomoxetine in children. However, safety and efficacy have not been established in children younger than 6 years of age. Most events were mild to moderate. Call your doctor right away if you or your child has any signs of heart problems such as chest pain, shortness of breath, or fainting while taking STRATTERA. Medication alone is generally insufficient and should be combined with behavioral therapy and parent training. STRATTERA was administered to 5382 children or adolescent patients with and 1007 adults with ADHD in clinical studies. During the ADHD clinical trials, 1625 children and adolescent patients were treated for longer than 1 year and 2529 children and adolescent patients were treated for over 6 months. Possible urinary retention and urinary hesitation. American Academy of Child and Adolescent Psychiatry. ipratropium
ADHD, are available and widely used, although their efficacy remains uncertain. If you have any questions about Strattera, please talk with your doctor, pharmacist, or other health care provider. The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables. Hyperactivity Disorder ADHD. Anyone considering the use of STRATTERA in a child or adolescent must balance this risk with the clinical need. Not known whether the risk extends to long-term use of the drug. 1 Balance risk of suicidality against the clinical need for the drug. 1 See Suicidality Risk under Cautions. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Dr. Peter Yellowlees: This article is selected from Medscape Best Evidence. I'm Dr. Peter Yellowlees. If used for extended periods, periodically reevaluate the usefulness of long-term therapy. Each item on the ADHDRS maps directly to one symptom criterion for ADHD in the -IV. Routine laboratory tests are not required. Very common 10% or more: Headache 20. Spencer T, Biederman J, Heiligenstein J et al. An open-label, dose-ranging study of atomoxetine in children with attention deficit hyperactivity disorder. J Child Adolesc Psychopharmacol. The medicine helps with your brain activity. Prescribers or other health professionals should inform patients, their families, and their caregivers about the benefits and risks associated with treatment with STRATTERA and should counsel them in its appropriate use. The prescriber or health professional should instruct patients, their families, and their caregivers to read the Medication Guide and should assist them in understanding its contents. Patients should be given the opportunity to discuss the contents of the Medication Guide and to obtain answers to any questions they may have. Strattera is available by prescription only. Methylphenidate may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. synthroid online over the counter synthroid
Check with your pharmacist about how to dispose of unused medicine. CGI-S remained the same or increased from study baseline and be eligible to enter an open-label study with atomoxetine. Marketed by: Lilly USA, LLC Indianapolis, IN 46285, USA. Revised: May 2017. Some MEDICINES MAY INTERACT with Strattera. Signs and symptoms of ADHD were evaluated using the investigator-administered Conners Adult ADHD Rating Scale Screening Version CAARS a 30-item scale. MAOI. Treatment with an MAOI should not be initiated within 2 weeks after discontinuing STRATTERA. The information on this page is not a substitute for the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that a drug or drug combination is safe, effective or appropriate for any given patient. Drugs. The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist. Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Do not consider WebMD User-generated content as medical advice. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences can be a helpful resource, but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. If you think you may have a medical emergency, call your doctor or dial 911 immediately. Avoid drinking alcohol, especially if you take Ritalin LA capsules. Alcohol may cause the methylphenidate to be released into the bloodstream too fast. purchase cheapest perindopril pharmacy australia
Call your doctor right away if you or your child have more than one of the following symptoms: a skin rash, dark urine, loss of appetite, yellow skin or eyes, flu-like symptoms, or right upper belly pain or tenderness. These could be symptoms of a serious liver problem. STRATTERA is not a controlled substance. Hyperactivity Disorder is unknown, but is thought to be related to selective inhibition of the pre-synaptic norepinephrine transporter, as determined in ex vivo uptake and depletion studies. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. This medicine has been prescribed for you only. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. Atomoxetine is well-absorbed after oral administration and is minimally affected by food. It is eliminated primarily by oxidative through the cytochrome P450 2D6 CYP2D6 enzymatic pathway and subsequent glucuronidation. Atomoxetine has a half-life of about 5 hours. A fraction of the population about 7% of Caucasians and 2% of African Americans are poor metabolizers PMs of CYP2D6 metabolized drugs. Ocular irritant; swallow capsules whole, do not open capsules or sprinkle contents on food. Strattera may affect the growth rate in CHILDREN and teenagers in some cases. They may need regular growth checks while they take Strattera. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. If your symptoms do not improve or if they become worse, check with your doctor. Store at room temperature away from moisture and heat. Taking MAO inhibitors with this medication may cause a serious possibly fatal drug interaction. Avoid taking MAO inhibitors isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, selegiline, tranylcypromine during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before and after treatment with this medication. Ask your doctor when to start or stop taking this medication. brand avelox levels avelox
Seizures - Seizures have been reported in the postmarketing period. At the 2 higher doses, improvements in ADHD symptoms were statistically significantly superior in STRATTERA-treated patients compared with placebo-treated patients as measured on the ADHDRS scale. Use with caution. May make side effects become worse. What brand names are available for atomoxetine? It is not your fault. Potential for increased plasma atomoxetine concentrations during concomitant therapy with CYP2D6 inhibitors in individuals with extensive metabolizer CYP2D6 phenotype concentrations may be similar to those achieved in poor metabolizers. Distributed into milk in rats; not known whether atomoxetine is distributed into human milk. 1 Caution if used in nursing women. In a new eight-week study of 101 children aged 5 to 6 with ADHD, the drug was safe and reduced some in children, according to reports by their parents and teachers. The capsule shells contain gelatin, sodium lauryl sulfate, and other inactive ingredients. Ritalin normal release tablets should taken at least 30 to 45 minutes before a meal. Extended-release Ritalin LA capsules or Ritalin SR tablets can be taken with or without food. Use Strattera as directed by your doctor. Check the label on the medicine for exact dosing instructions. At first, 18 to 36 milligrams mg once a day in the morning. Your doctor may adjust your dose as needed. However, the dose is usually not more than 72 mg per day.
Romance" by Jonathan Halverstadt, "You Mean I'm Not Lazy, Stupid or Crazy? At first, 40 milligrams mg once a day. The dose is increased after a minimum of 3 days to a total daily dose of 80 mg as a single dose in the morning or divided in 2 doses morning and late afternoon. Your doctor may adjust your dose as needed. However, the dose is usually not more than 100 mg per day. STRATTERA may be taken with or without food. The active substance is atomoxetine hydrochloride. If psychotic symptoms occur, consider causal relationship to atomoxetine, and discontinue therapy as appropriate. PMs. 4-Hydroxyatomoxetine is primarily formed by CYP2D6, but in PMs, 4-hydroxyatomoxetine is formed at a slower rate by several other cytochrome P450 enzymes. N-Desmethylatomoxetine is formed by CYP2C19 and other cytochrome P450 enzymes, but has substantially less pharmacological activity compared with atomoxetine and circulates in plasma at lower concentrations 5% of atomoxetine concentration in EMs and 45% of atomoxetine concentration in PMs. The major oxidative metabolite formed, regardless of CYP2D6 status, is 4-hydroxyatomoxetine, which is glucuronidated. phene.info microzide
Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women. All pediatric patients being treated with STRATTERA should be monitored appropriately and observed closely for clinical worsening, suicidality, and unusual changes in behavior, especially during the initial few months of a course of drug therapy, or at times of dose changes, either increases or decreases. Food and Drug Administration. FDA alert for healthcare professionals. Atomoxetine marketed as Strattera. Rockville, MD; September 2005. From FDA Website. Cardiovascular system - QT prolongation, syncope. It may help if you read small bits at a time. In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. The dosage is based on your medical condition, response to treatment, and other drugs you may be taking. Be sure to tell your doctor and pharmacist about all the products you use including prescription drugs, nonprescription drugs, and herbal products. Do not increase your dose or take this drug more often than directed. This medicine may make you more drowsy, dizzy, less alert, or lightheaded than normal. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert. Dizziness, lightheadedness, or fainting may also occur when you get up suddenly from a lying or sitting position. Getting up slowly or lying down for awhile may help. In two post-marketing, double-blind, placebo-controlled trials, it has been demonstrated that treating patients with ADHD and comorbid anxiety disorders with STRATTERA does not worsen their anxiety. The following adverse reactions have been identified during post approval use of STRATTERA. Unless otherwise specified, these adverse reactions have occurred in adults and children and adolescents. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. The pharmacokinetics of atomoxetine have been evaluated in more than 400 children and adolescents in selected clinical trials, primarily using population pharmacokinetic studies. Single-dose and steady-state individual pharmacokinetic data were also obtained in children, adolescents, and adults. Some stimulants have caused sudden death in certain people. Do not use this medicine together with a drug for depression called a MAO inhibitor. Each capsule contains atomoxetine HCl equivalent to 10, 18, 25, 40, 60, 80, or 100 mg of atomoxetine. The metabolite N-desmethylatomoxetine HCl was negative in the Ames Test, mouse lymphoma assay, and unscheduled DNA synthesis test. buy pantozol tablets online shopping
Strattera may not be right for you or your child. Atomoxetine is rapidly absorbed after oral administration, with absolute bioavailability of about 63% in EMs and 94% in PMs. Maximal plasma concentrations Cmax are reached approximately 1 to 2 hours after dosing. Two adult atomoxetine subjects and no placebo subjects discontinued from controlled clinical trials because of urinary retention. A complaint of urinary retention or urinary hesitancy should be considered potentially related to atomoxetine. XR extended-release suspension, shake the bottle well for at least 10 seconds before measuring each dose. Use only the oral dosing dispenser provided in the package to get the right dose. You may take it with or without food. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets. Inattentive type. Formerly called attention deficit disorder ADD. These children are not overly active. They do not disrupt the classroom or other activities, so their symptoms might not be noticed. olmesartan 500 mg at walmart
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. STRATTERA dose was not superior to placebo. Can discontinue atomoxetine without tapering dosage. Monitor growth of pediatric patients receiving atomoxetine. This medication may raise your blood pressure. Check your blood pressure regularly and tell your doctor if the results are high. Mechanism of action in the management of ADHD appears to be related to selective inhibition of the presynaptic norepinephrine transporter. rifampicin
Strattera in children, he says. For example, children who did not respond to stimulants and those who may be unable to take them due to medical problems or in the home may benefit, he says. If I run out then I have to make do without! If you get any side effects, talk to your doctor or pharmacist. What other important information should I know about Strattera? Adderall is also a man-made stimulant and was first approved in 1996 and is thought to work in ADHD by increasing the concentration of two neurotransmitters dopamine and norepinephrine in the brain. Both Strattera and Adderall are approved to treat ADHD, although Adderall is also approved to treat narcolepsy. Hyperactivity Disorder Rating Scale-IV-Parent Version: Investigator administered and scored. Children show both hyperactive and impulsive behavior, but for the most part, they are able to pay attention. Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
They will also be done when the dose is changed. Clinical study data in over 2000 children, adolescents, and adults with ADHD and over 1200 adults with depression showed only isolated incidents of drug diversion or inappropriate self-administration associated with STRATTERA. There was no evidence of symptom rebound or adverse reactions suggesting a drug-discontinuation or withdrawal syndrome. This Medication Guide has been approved by the US Food and Drug Administration. Dizziness, lightheadedness, or fainting may occur, especially when you get up suddenly from a lying or sitting position. These symptoms are more likely to occur when you begin taking this medicine or when the dose is increased. Getting up slowly or lying down for awhile may help. The effect of STRATTERA on QTc prolongation was evaluated in a randomized, double-blinded, positive-moxifloxacin 400 mg and placebo-controlled, cross-over study in healthy male CYP2D6 poor metabolizers. A total of 120 healthy subjects were administered STRATTERA 20 mg and 60 mg twice daily for 7 days. Rare postmarketing cases of priapism, defined as painful and nonpainful penile erection lasting more than 4 hours, have been reported for pediatric and adult patients treated with STRATTERA. The parents or guardians of pediatric patients taking STRATTERA and adult patients taking STRATTERA should be instructed that priapism requires prompt medical attention. Use and dose must be determined by your doctor. Michelson D, Adler L, Spencer T et al. Atomoxetine in adults with ADHD: two randomized, placebo-controlled studies. Biol Psychiatry. This medicine may cause slow growth. If your child is using this medicine, the doctor will need to keep track of his height and weight to make sure that he is growing properly. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. What are possible side effects of STRATTERA? How should I take Ritalin? epoetin-alfa care cost
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Do not try to open the capsules or take them apart. If a capsule breaks, do not touch it. Wash your hands and any surfaces that touched a broken capsule. Do not get Strattera in your eye; it may irritate your eye if you do. If you get Strattera in your eyes or nose, rinse at once with cool water. Strattera can cause liver injury in some patients. Call your doctor right away if you or your child has itching, right upper belly pain, dark urine, yellow skin or eyes, or unexplained flu-like symptoms. Tell your doctor if you or your child is pregnant, planning to become pregnant, or breastfeeding. Nervous system disorders - Hypoaesthesia; paraesthesia in children and adolescents; sensory disturbances; tics.
Your doctor will talk to you about these sides effects. It is generally agreed that pharmacological treatment of ADHD may be needed for extended periods. Have or have had a rare tumor called pheochromocytoma.
Are taking or have taken within the past 14 days an anti-depression medicine called a monoamine oxidase inhibitor or MAOI. STRATTERA and methylphenidate were compared with placebo. STRATTERA was administered as a divided dose in the early morning and late afternoon after school and titrated on a weight-adjusted basis according to clinical response. If you are taking the chewable tablet, drink at least 8 ounces of water or other liquid when you chew the tablet. Take it preferably 30 to 45 minutes before meals. Methylphenidate may cause serious heart or blood vessel problems. This may be more likely in patients who have a family history of heart disease. Check with your doctor right away if you or your child has chest pain, shortness of breath, fainting, or a fast, irregular heartbeat while using this medicine.
MAOI. Some cases presented with features resembling neuroleptic malignant syndrome. Strattera comes with an extra patient information sheet called a Medication Guide. Read it carefully. Read it again each time you get Strattera refilled. Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.